The top seed won two matches on Thursday to advance to the last eight at the RCA Tennis Championships in Indianapolis.
The American No. 2 scored a fluent win over Robert Kendrick U.S. Men's Clay Court Championships.
Andy Roddick beat Vince Spadea 6-1, 6-3, while Guillermo Coria beat Fernando Gonzalez 4-6, 7-6, 6-1 in the semi-finals of the Nasdaq-100 Open.
The top seed toiled for more than two hours to overcome Todd Martin 7-6, 1-6, 7-5 in the first round of the Kroger St Jude tournament.
Agassi clattered former Melbourne Park runner-up Thomas Enqvist 6-0 6-3 6-3 in a breathtaking display at the Australian Open.
Sweden's Jonas Bjorkman defeated the world number one 6-3, 6-4 in just over an hour at the Qatar Open.
Andy Roddick blew away fellow American Robby Ginepri 6-2, 6-3 on Thursday to move into the third round of the Memphis Championships.
"There have been moments for optimism - plenty. And on the men's side, not as much."
A new coach, a new work ethic and renewed belief in his game took Andy Roddick agonisingly close to a Wimbledon title on Sunday and while the experience left him utterly drained the American will not turn back the clock now.
Former champion Andy Roddick will take centre stage at the US Open on Friday, perhaps for the last time, when he plays rising Australian Bernard Tomic for a place in the third round.
Roger Federer was forced to dig deep during a 4-6, 7-6, 6-4 win Andy Roddick in the Masters Cup.
Andy Roddick swept to his first grasscourt title on Sunday after thrashing Sebastien Grosjean 6-3, 6-3.
Top seed Robin Soderling underlined his credentials as an Australian Open contender by overpowering defending champion Andy Roddick 6-3, 7-5 to win the Brisbane International on Sunday.
Andy Roddick stayed on course for a fifth Queen's Club title on Thursday when fellow American Mardy Fish retired after one set of their Centre Court clash.
American Andy Roddick romped past lucky loser Edouard Roger-Vasselin 6-2, 6-4 to reach the third round of the Winston-Salem Open on Tuesday, and get his US Open preparations back on track.
In the other semi-final at the San Jose Open, German sixth seed Benjamin Becker, who upset Marat Safin will take on Ivo Karlovic.
The top seed was drawn against Fernando Gonzalez in the first round of next week's Australian Open.
Big-serving American Andy Roddick eased past former world No 1 Juan Carlos Ferrero to make the semi-finals of the China Open on Friday, along with Germany's Bjorn Phau, Israel's Dudi Sela and Rainer Schuettler of Germany.
America's Andy Roddick safely negotiated the opening round of the ATP tournament in Poertschach, Austria, on Monday, seeing off local wildcard Alexander Peya.
Andy Roddick beat Fabrice Santoro of France 6-2, 6-2, 6-2 to complete the men's first round at the US Open.
Swede Robin Soederling outgunned top seed Andy Roddick in the quarter-finals of the Memphis Championship.
Andy Roddick and number two Tommy Haas moved closer to a showdown at the Legg Mason Tennis Classic with third-round victories.
Andy Roddick beat impressive Japanese teenager Kei Nishikori 6-2, 6-4 in the second round of the San Jose Open.
Andy Roddick warmed up for the Australian Open in ideal fashion with a 7-5, 6-3 win over Marcos Baghdatis.
American Andy Roddick survived a determined fight back from defending champion Radek Stepanek to win the Brisbane International final on Sunday.
The US ace broke his record with a 155mph (249kph) serve as the U.S. took a 2-0 lead over Belarus in their Davis Cup semi-final.
Top seed and two-times champion Andy Roddick moved into the last eight of the Indianapolis Championships with a 6-3 6-2 win over Russia's Evgeny Korolev on Wednesday.
Andy Roddick entered the fourth round with a 6-1, 6-2, 6-2 win over France's Julien Benneteau
American sixth seed Andy Roddick will play unseeded Spaniard Feliciano Lopez in the final of the Dubai Championships on Saturday. Roddick overcame third seed Novak Djokovic of Serbia 7-6, 6-3 while Lopez recovered from 2-5 in the final set to beat fifth-seeded Russian Nikolay Davydenko 6-4, 4-6, 7-5.
The American staged a great escape with a dramatic 4-6, 7-,6 7-6 win over France's Nicolas Mahut in the final.
Defending champion Davydenko, the top seed, struggled to keep pace with Argentina's Juan Monaco and slumped to a 6-2, 6-7, 6-4 defeat at the Poertschach International.
Novak Djokovic scraped past Robin Soderling 3-6, 6-4, 6-3 at the Rome Masters.
They reached the fourth round of the Pacific Life Open on Monday.
